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Following a screening period of up to 30 days, all eligible participants entered a run-in period during which they were stabilized on 12/3 mg of buprenorphine/naloxone SL film (hereafter referenced as SL BUP) once daily for a minimum of 7 days and a maximum of 14 days before BUP-XR injection (Day 14 to Day 1, Supplementary Fig

Multiple studies done by Lenzi A et al (a research group in Italy) which were published in The Oxford Journal of Human Reproduction, Frontiers in BioScience, Archives of Andrology, and Contraception , came to the following conclusions in regards to sperm, oxidative stress (inflammation), and glutathione