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The effect of curcumin on TGF-1 in cancer therapy is dose- and time-dependent manner (Celik et al., 2018)

Doing physical therapy exercises

This may vary from twice weekly to once every 2-4 weeks (source: The basics of treatment It is not understood why certain patients require more frequent B12 treatment

However, unguided self-medication has many potential risks such as incorrect self-diagnosis, dangerous drug interactions, incorrect manner of administration, severe adverse reactions, and masking of severe disease