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Accordingly, the unique genomic map of SARS-CoV-2 virus and the extent of its mediated virushost proteinprotein interactions that trigger human metabolic reprogramming and dysregulation (HMRD) in favor of the virus life cycle, defines the ultimate severity and fate of COVID-19 23,24,25,26

For decades, drugs targeting CPT1A have been the focus of research on diseases like type 2 diabetes (T2D), obesity, and other disorders ( CPT1A inhibitors The efforts to study the molecular mechanisms of CPT1A inhibition in disease intervention have increased in recent years due to the association with cancer (Schlaepfer et al., 2014)