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Ferroptosis, a unique form of regulated cell death characterized by iron-dependent lipid peroxidation, significantly impacts immune cell function and inflammatory responses, contributing to the autoimmune disease process (87, 88, 141, 199, 200)

Therefore, intracellular GSH depletion or GPX4 inactivation induced by various factors will decrease the clearance rate of toxic lipid peroxides and result in ferroptosis

10.1016/j.ajpath.2020.08.014 61 SmithH

Within the intricate world of the eye, these computational image analyses are reshaping our understanding of retinal aging and ailments, offering the chance for swift, early screening and targeted intervention

PloS one 10 (6), e0130353