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Hydroxyl radical is formed by a rather slow reaction via the reaction of ferrous iron with hydrogen peroxide, but is so reactive that it can only diffuse about the diameter of a typical protein (586)

Free radicals in the human body that are not cleared fast enough can damage cells and eventually lead to local apoptosis and in turn global aging of the body

Cummins CB, Wang X, Nunez Lopez O, Graham G, Tie H-Y, Zhou J et al (2018) Luteolin-mediated inhibition of hepatic stellate cell activation via suppression of the STAT3 pathway

We therefore measured liver TC and TG levels in mice and concordantly illustrated that there were no significant alterations in AAV_Abcc4_RNAi group fed with a normal-chow diet (NCD) (Fig