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One study of post-menopausal women with PCOS using 4g/day of myo-inositol also found a reduction in fasting glucose, fasting insulin and HOMA-IR ( Inositol supplements in postmenopausal women with metabolic syndrome 2012 )

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Our findings suggest that PC may alleviate PE by restoring angiogenic balance and modulating metabolic homeostasis

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It behaves almost like an endocrine organ, constantly secreting inflammatory cytokines and hormones that disrupt normal metabolic function