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Figure 2: Changes in rotation asymmetry expressed as the percentage of the animals rotation in the direction of the damage relative to rotations in both directions

Gill P, Richards K, Cho WC, Nagarajan P, Aung PP, Ivan D, Curry JL, Prieto VG, Torres-Cabala CA

The differences in the proportion of patients with ALT and/or AST increase across these cohorts may be due to varying cohort sizes, different characteristics of the patients included, and conservative real-world practices in the US, such as stepwise dose titration during treatment initiation and treatment interruption at a lower level of ALT or AST elevation of 3 ULN, versus the per-protocol procedures in the French EAP cohorts

The general recommended dose of bimekizumab for adult patients with HS is 320 mg (given as 2 subcutaneous injections of 160 mg each) every 2 weeks up to week 16 and every 4 weeks thereafter (49)

1, Supplementary Tables 1, 2, Supplementary Note 1), we constructed E