Embodiment 8 of this disclosure are compounds of Formula I, or any one of Embodiments 1-7 or a pharmaceutically acceptable salt of any of the foregoing, wherein R 1 Embodiment 9 of this disclosure are compounds of Formula I, or any one of Embodiments 1-8 or a pharmaceutically acceptable salt of any of the foregoing, wherein R 2 is Embodiment 28 of this disclosure are compounds of Formula I, or Embodiments 1-12, or 27, or a class thereof, or a pharmaceutically acceptable salt of any of the foregoing, wherein R 2 is Embodiment 29 of this disclosure are compounds of Formula I, or Embodiments 1-11, 13, or 27, or a class thereof, or a pharmaceutically acceptable salt of any of the foregoing, wherein R 2 is Embodiment 30 of this disclosure are compounds of Formula I, or Embodiments 1-11, 14, or 27, or a class thereof, or a pharmaceutically acceptable salt of any of the foregoing, wherein R 2 is Embodiment 31 of this disclosure are compounds of Formula I, or Embodiments 1-11, 14, or 27, or a class thereof, or a pharmaceutically acceptable salt of any of the foregoing, wherein R 2 is Embodiment 32 of this disclosure are compounds of Formula I, or Embodiments 1-11, 14, or 27, or a class thereof, or a pharmaceutically acceptable salt of any of the foregoing, wherein R 2 is Embodiment 33 of this disclosure are compounds of Formula I, or Embodiments 1-11, 14, or 27, or a class thereof, or a pharmaceutically acceptable salt of any of the foregoing, wherein R 2 is Embodiment 34 of this disclosure are compounds of Formula I, or Embodiments 1-11, 14, or 27, or a class thereof, or a pharmaceutically acceptable salt of any of the foregoing, wherein R 2 is Embodiment 35 of this disclosure are compounds of Formula I, or any one of Embodiments 1-34, or a pharmaceutically acceptable salt of any of the foregoing, wherein R 3 is Embodiment 48 of this disclosure are compounds of Formula I, or any one of Embodiments 1-38 or 47, or a pharmaceutically acceptable salt of any of the foregoing, wherein R 3 is Embodiment 49 of this disclosure are compounds of Formula I, or any one of Embodiments 1-38 or 47, or a pharmaceutically acceptable salt of any of the foregoing, wherein R 3 is Embodiment 50 of this disclosure are compounds of Formula I, I-a, or I-b, or any one of Embodiments 1-38 or 47, or a pharmaceutically acceptable salt of any of the foregoing, wherein R 3 is Embodiment 51 of this disclosure are compounds of Formula I, I-a, or I-b, or any one of Embodiments 1-38 or 47, or a pharmaceutically acceptable salt of any of the foregoing, wherein R 3 is Embodiment 52 of this disclosure are compounds of Formula I, I-a, or I-b, or Embodiments 1-51, or a class thereof, or a pharmaceutically acceptable salt of any of the foregoing, wherein R 4 is H

Fradin-Read, MD, MPH, Founder of VitaLife-MD Integrative Medical Practice How exciting it is that my distinguished colleague Dr
HMGB1, high mobility group B1
Wound healing research consistently shows accelerated closure and improved collagen density versus controls
But it does not bypass the glycine requirement at step two