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Women using oral contraceptives should be counseled about this potential interaction and may need to consider alternative or additional contraceptive methods, particularly during the initial weeks of treatment when gastric emptying effects may be most pronounced

In addition, adults who are immunosuppressed should be vaccinated for pneumococcus and meningococcus

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Poster Session II - ACUTE ISCHEMIC STROKE MANAGEMENT 01.00 - ACUTE ISCHEMIC STROKE MANAGEMENT - 01.06 - IMAGING - Hyperacute P655 - ESOC25-958 FEMALE PATIENTS WITH LARGE VESSEL OCCLUSION SHOW MORE FAVORABLE PERFUSION METRIC PROFILES Irene Rosa 1 , Salvatore Rudilosso, Alejandro Rodrguez Vzquez 1 , Antonio Doncel-Moriano 1 , Carlos Laredo 2 , Andrea Cabero-Arnold 2 , Laura Llull, Arturo Ren 1 , Sergio Amaro, Xabier Urra 1 , Angel Chamorro 1 1 Hospital Clnic, Barcelona, Spain, 2 Fundaci de Recerca Clnic Barcelona - Institut d'Investigacions Biomdiques August Pi i Sunyer, Barcelona, Spain Background and Aims: Stroke severity and outcomes tend to be worse in women than in men, though the underlying reasons are unclear

Pernicious anaemia, a condition marked by the deficiency of vitamin B12 due to the inability of the body to absorb it, necessitates lifelong treatment to manage symptoms and prevent complications